A highly ionized drug :
A. Is excreted mainly by the kidneys
B. Corsses the placental barrier easily
C. Is well absorbed from the intestine
D. Is highly protein bound
Correct answer : A. Is excreted mainly by the kidneys
Highly ionized drugs are lipid insoluble. Hence they are poorly absorbed by the intestine. They cannot cross the placental barrier easily. And since they are not reabsorbed in the renal tubules, they are excreted in urine.