Pharmacology – MCQ 114 – Features of ionized drugs

A highly ionized drug :
A. Is excreted mainly by the kidneys
B. Corsses the placental barrier easily
C. Is well absorbed from the intestine
D. Is highly protein bound

Correct answer : A. Is excreted mainly by the kidneys

Highly ionized drugs are lipid insoluble. Hence they are poorly absorbed by the intestine. They cannot cross the placental barrier easily. And since they are not reabsorbed in the renal tubules, they are excreted in urine.

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