Most common cause of Down’s syndrome – Pathology MCQ

Most common cause of Down’s syndrome is?

A. Translocation

B. Mosaicism

C. Paternal nondisjunction

D. Maternal nondisjunction

 

Correct answer : D. Maternal nondisjunction

Maternal nondisjunction in meiosis I is the most common cause of Down’s syndrome (95% of total cases)

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