Most potent fluoroquinolone against Mycobacterium leprae is?
Correct answer : C. Moxifloxacin
- Ciprofloxacin has poor activity against Mycobacterium leprae.
- Ofloxacin, Pefloxacin, Moxifloxacin and Sparfloxacin have high level of activity against Mycobacterium leprae.
- Among them, Moxifloxacin is the most potent.
Ref: Essentials of Medical Pharmacology, K D Tripathi, 7th ed, p782.
Image credits: CDC Public Health Image Library (PHIL) #2123. https://en.wikipedia.org/wiki/File:Mycobacterium_leprae.jpeg