Obstetrics & Gynaecology – MCQ 67 – Biochemical test to detect open spina bifida

Which one of the following biochemical parameters is the most sensitive to detect open spina bifida?
A. Maternal serum alpha fetoprotein
B. Amniotic fluid alpha fetoprotein
C. Amniotic fluid acetyl cholinesterase
D. Amniotic fluid glucohexaminase

Correct answer : C. Amniotic fluid acetyl cholinesterase