Ophthalmology – MCQ 39 – Malignancy in survivors of retinoblastoma

The most common second malignancy in survivors of retinoblastoma is:
A. Thyroid cancer
B. Nasopharyngeal carcinoma
C. Optic glioma
D. Osteosarcoma

Correct answer : D. Osteosarcoma

Osteosarcoma and retinoblastoma both can arise in those with RB gene mutation.

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