Orthopaedics – MCQ 10 – 60 yrs old male with bony abnormality at upper tibia and hearing loss

60 yrs old male with bony abnormality at upper tibia associated with sensorineural hearing loss. On laboratory examination serum alkaline phosphatase levels are (440 mU/l) elevated and serum Ca and PO4 are normal. Skeletal survey shows ivory vertebrae and cotton wool spots in x-ray skull. Diagnosis is :
a) Fibrous dysplasia
b) Paget disease
c) Osteosclerotic metastasis
d) Osteoporosis

Correct answer : b) Paget disease

The age, clinical features and investigation findings are characteristic of Paget’s disease.

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