The coagulation profile in a 13-year old girl with Menorrhagia having von Willebrands disease is:
A. Isolated prolonged PTT with a normal PT
B. Isolated prolonged PT with a normal PTT
C. Prolongation of both PT and PTT
D. Prolongation of thrombin time
Correct answer : A. Isolated prolonged PTT with a normal PT
In VWF, there is impairment of intrinsic coagulation pathway. Hence there is isolated prolonged PTT.