Pharmacology – MCQ 27 – Methotrexate is used in high doses in?

Methotrexate is used in high doses in:
A. Osteosarcoma
B. Retinoblastoma
C. Rhabdomyosarcoma
D. Ewing’s sarcoma

Correct answer : A. Osteosarcoma

Methotrexate is used in high doses (with leucovorin rescue) for treatment of osteosarcoma, hematological malignancies and brain tumours.