Pharmacology – MCQ 90 – Ionized drug

A highly ionized drug:
A. Is excreted mainly by the kidney
B. Can cross the placental barrier easily
C. ls well absorbed from the intestine
D. Accumulates in the cellular lipids

Correct answer : A. Is excreted mainly by the kidney

Highly ionized drugs are lipid insoluble. Hence their movement across cell membrane is decreased. (Resulting in decreased absorption, decreased movement across placenta, decreased reabsorption in kidney etc…)

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