Regarding somatomedin, which is true?
A. Reduced glucose oxidation in fat
B. Increases chondrogenesis
C. Activity is increased in protein deficiency
D. Activity is increased by glucocorticoids
Correct answer : B. Increases chondrogenesis
Structure of somatomedin C (Insulin-like growth factor 1)
- Somatomedin increases glucose oxidation in fat.
- Activity of somatomedin is reduced by protein deficiency and glucocorticoids.
- It has insulin like effect on tissues and causes lipolysis and increased glucose and amino acid transport by muscle.
Ref: Textbook of Physiology, A K Jain, 3rd edition, Volume 2, page 670.
Image credits: Author: Emw. Licensed under the Creative Commons Attribution-Share Alike 3.0 Unported license. https://en.wikipedia.org/wiki/File:Protein_IGF1_PDB_1bqt.png
