Role of FSH regulatory peptides in delayed onset of puberty is males

  • The onset of puberty in males is delayed compared to that in females
  • This is due to delayed rise in FSH levels in males
  • FSH levels are under the control of FSH regulatory peptides. They are:
    • Inhibin
    • Follistatin
    • Activin A
  • Of these, Inhibin and Follistatin decreases FSH levels
  • Activin A increases FSH production
  • In males, the FSH regualtory peptides act is such a way as to delay the onset of puberty

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