Severe muscle weakness is seen in? – Medicine MCQ

Severe muscle weakness is seen in?
A. Cori disease
B. Andersen disease
C. McArdle disease
D. Tarui disease

Correct answer : B. Andersen disease

Glycogen storage disease liver - Cori diseaseGlycogen storage disease – liver biopsy

  • Andersen disease is a type 4 glycogen storage disease.
  • It occurs due to deficiency of brancher enzyme.
  • It usually presents in infancy with severe muscle weakness.
  • Cirrhosis can also occur.

Ref: Davidson’s Principles and Practice of Medicine, 22nd edition, p450
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