Sibai regimen

• Sibai regimen is an intravenous magnesium sulphate regimen for treatment of eclampsia
• It was introduced by Sibai et al in 1990
• Loading dose – 6g IV given over 20 minutes
• Maintenance dose – 2-3g IV every hour

Maternal and fetal outcome after treatment with Sibai regimen:

• In a study published by Sibai et al in 1990, treatment of eclampsia with Sibai regimen had a maternal mortality of 0.5% and a perinatal mortality of 5%.