Sibai regimen

  • Sibai regimen is an intravenous magnesium sulphate regimen for treatment of eclampsia
  • It was introduced by Sibai et al in 1990
  • Loading dose – 6g IV given over 20 minutes
  • Maintenance dose – 2-3g IV every hour

Maternal and fetal outcome after treatment with Sibai regimen:

  • In a study published by Sibai et al in 1990, treatment of eclampsia with Sibai regimen had a maternal mortality of 0.5% and a perinatal mortality of 5%.

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