Most specific marker for neural tube defects – Obstetrics MCQ

Most specific marker for neural tube defects is?
A. Alpha-fetoprotein
B. Unconjugated estriol
C. Acetylcholinesterase
D. Pseudocholinesterase

Correct answer : C. Acetylcholinesterase

Both alpha-fetoprotein and acetylcholinesterase in amniotic fluid are markers for neural tube defects. But acetylcholinesterase is the most specific marker.

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