Triad of skin lesions, mononeuritis multiplex and eosinophilia – Medicine MCQ
Triad of skin lesions, asymmetric mononeuritis multiplex and eosinophilia are seen in?
A. Cryoglobulinemic vasculitis
B. Polyarteritis nodosa
C. Churg Strauss Syndrome
D. Giant cell arteritis
Correct answer : C. Churg Strauss Syndrome
Churg Strauss Syndrome
- Churg Strauss Syndrome is a small vessel vasculitis.
- Biopsy of affected site reveals small vessel vasculitis with eosinophilic infiltration of vessel wall.
Cryoglobulinemic vasculitis
- Cryoglobulinemic vasculitis presents with rash over lower limbs, arthralgia, Raynaud’s phenomenon and neuropathy
Polyarteritis nodosa
- Polyarteritis nodosa presents with fever, myalgia, arthralgia, multisystem involvement and palpable purpura.
Giant cell arteritis
- Cardinal symptom of giant cell arteritis is headache localised to temporal or occipital region.
- Visual disturbances can occur.
- Catastrophic presentation is with blindness in one eye.
- It is commonly associated with polymyalgia rheumatica.
Ref: Davidson’s Principles and Practice of Medicine, 22nd ed, p1117-1119
