True regarding Drotaverine? – Pharmacology MCQ

Which of the following is true regarding Drotaverine?
A. M3 selective muscarinic antagonist
B. Causes smooth muscle contraction
C. Causes anticholinergic side effects
D. Inhibits phosphodiesterase-4

Correct answer : D. Inhibits phosphodiesterase-4

DrotaverineDrotaverine

  • Drotaverine is a smooth muscle antispasmodic.
  • Mechanism of action is inhibition of phosphodiesterase-4 selective for smooth muscle.
  • It causes smooth muscle relaxation.
  • It does not have anticholinergic side effects.

Ref: Essentials of Medical Pharmacology, K D Tripathi, 7th ed, p118.
Image credits: https://en.wikipedia.org/wiki/File:Drotaverine.svg