Which is a true statement regarding inhibin? – Physiology MCQ

Which is a true statement regarding inhibin?
A. Increases the secretion of GnRH.
B. Molecular weight is between 5000 and 10,000.
C. It is secreted by hypothalamus.
D. It is a glycoprotein.

Correct answer : D. It is a glycoprotein.

  • Inhibin is secreted by the sertoli cells in males and by the granulosa cells in females.
  • It inhibits the secretion of Gonadotrophin Releasing Hormone.
  • It is a glycoprotein with molecular weight between 10,000 and 30,000.
  • It has potent inhibitory feedback effect on the anterior pituitary gland which in turn provides negative feedback mechanism for the control of spermatogenesis.

Ref: Textbook of Medical Physiology, Guyton and Hall, 11th edition, page 1007.

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