Which of the following is true regarding RU 486? – Obstetrics MCQ

Which of the following is true regarding RU 486?
A. Prevents fertilization
B. Has affinity for estrogen receptors
C. Single dose of 10mg prevents pregnancy in 90% cases
D. Causes delayed menstruation

Correct answer : D. Causes delayed menstruation

  • RU 486 (mifepristone) does not prevent fertilization.
  • It has affinity for progesterone receptors.
  • It blocks the action of progesterone on the endometrium.
  • It prevents implantation by causing sloughing and shedding of decidua.
  • Single dose of 10mg prevents pregnancy in 99.1% cases.

Ref: Shaw’s Textbook of Gynaecology, 15th edition, p237.

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