Why oral bile acid therapy is contraindicated in radio opaque gall stones?

  • Bile acids help dissolve gall stones by decreasing the levels of cholesterol available for stone formation
  • But radio opaque stones contain calcium in addition to cholesterol – dissolution of which is not possible
  • Hence, bile acid therapy is contraindicated in radio opaque gall stones

Reference:
Diseases of the liver and biliary system By Sheila Sherlock, Sheila Sherlock (Dame.), James Dooley

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