AIIMS May 2012 – MCQ 7

Mechanism of development of edema in nephrotic syndrome is?
A. Sodium and water retention
B. Loss of proteins
C. Hyperlipidemia
D. Increased venous pressure

Correct answer : B. Loss of proteins

(Repeat AIIMS Nov 2010)

Explanation: In nephrotic syndrome, there is loss of proteins through the glomeruli. This results in hypoalbuminemia and decreased plasma oncotic pressure. Thus fluid moves into the extravascular compartment – development of edema.

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