Amoxycillin is an extended spectrum aminopenicillin. But it is not active against penicillinase producing organism. Clavulanic acid is a penicillinase inhibitor which initially reversibly and then irreversibly inhibits penicillinase 2-5 except cephalosporinase. So this drug combination has a synergistic action.
Copyright © 2008-2018 PG Blazer.
Disclaimer : Although every effort is made to ensure the accuracy of the material, the authors will not be held responsible for any inadvertent errors. The information in this site is provided only as a resource for PG entrance aspirants, and is not to be used for any diagnostic or treatment purposes.