Bruch's membrane

  • It is the innermost layer of the choroid
  • 2-4 microns in thickness
  • elastic mucoprotein membrane
  • Lies between the retina pigment epithelium and the layer of choriocapillaris
  • Alternate name – lamina vitrea

Development – outer part develops from the mesoderm while the inner part develops from ectoderm

It is divided into 5 layers:

  1. Outer choroidal layer composed of endothelial cells of the choriocapillaris
  2. Outer collagenous zone (OCZ)
  3. Layer of fenestrated elastic fibers
  4. Inner collagenous zone (ICZ)
  5. Basement membrane of Retinal pigment epithelium

Clinical importance:

  • The bruch’s membrane is involved in the pathogenesis of age related macular degeneration

Add a Comment

Your email address will not be published. Comments will be displayed only after moderation.

Read previous post:
Structures related to bed of tonsil

The tonsil is separated from its bed by loose areolar tissue. The structures forming the bed of the tonsil are:...

Close