Which is associated with vaginal carcinoma in female offspring?
C. ACE inhibitors
Correct answer : A. Diethylstilbestrol
- Diethylstilbestrol can cause vaginal clear cell adenocarcinoma in girls and young women exposed to it in utero.
- Phenytoin can cause fetal hydantoin syndrome which is characterised by hypoplasia of the phalanges, cleft lip, cleft palate and microcephaly.
- Indomethacin / aspirin can cause premature closure of the ductus arteriosus.
Ref: KDT 7th, p89
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