Pathology – MCQ 91 – Inheritance of Kinky hair disease

Kinky hair disease is a disorder where an affected child has peculiar white stubby hair, does not grow, brain degenration is seen and dies by age of two years. Mrs A is hesitant about having children because her two sisters had sons who had died from kinky hair disease. Her mother’s brother also died of the same condition. Which of the following is the possible mode of inheritence in her family?
A. X-linked recessive
B. X-linked dominant
C. Autosomal recessive
D. Autosomal dominant

Correct answer : A. X-linked recessive

Only males are affected. Females are carriers.