Most specific marker for neural tube defects – Obstetrics MCQ
Most specific marker for neural tube defects is?
A. Alpha-fetoprotein
B. Unconjugated estriol
C. Acetylcholinesterase
D. Pseudocholinesterase
Correct answer : C. Acetylcholinesterase
Both alpha-fetoprotein and acetylcholinesterase in amniotic fluid are markers for neural tube defects. But acetylcholinesterase is the most specific marker.