True regarding Drotaverine? – Pharmacology MCQ
Which of the following is true regarding Drotaverine?
A. M3 selective muscarinic antagonist
B. Causes smooth muscle contraction
C. Causes anticholinergic side effects
D. Inhibits phosphodiesterase-4
Correct answer : D. Inhibits phosphodiesterase-4
- Drotaverine is a smooth muscle antispasmodic.
- Mechanism of action is inhibition of phosphodiesterase-4 selective for smooth muscle.
- It causes smooth muscle relaxation.
- It does not have anticholinergic side effects.
Ref: Essentials of Medical Pharmacology, K D Tripathi, 7th ed, p118.
Image credits: https://en.wikipedia.org/wiki/File:Drotaverine.svg