Which of the following is seen in Churg-Strauss syndrome? – Medicine MCQ

Which of the following is seen in Churg-Strauss syndrome?
A. Sinusitis
B. Raynaud’s phenomenon
C. Allergic rhinitis
D. Epistaxis

Correct answer : C. Allergic rhinitis

Eosinophilic vasculitis in Churg Strauss syndromeEosinophilic vasculitis in Churg Strauss syndrome

  • Churg-Strauss syndrome is a small vessel vasculitis.
  • The acute presentation includes skin lesions, eosinophilia and asymmetric mononeuritis multiplex.
  • There can be a prodromal period lasting many years in which the patient can have allergic rhinitis, nasal polyposis and asthma.
  • Treatment is by high dose steroids and cyclophosphamide.
  • Maintenance therapy is by low dose steroids, azathioprine, methotrexate and mycophenolate mofetil.

Ref: Davidson’s Principles and Practice of Medicine, 22nd edition, p1118
Image credits: Nephron. Licensed under the Creative Commons Attribution-Share Alike 3.0 Unported license. https://en.wikipedia.org/wiki/File:Churg-Strauss_syndrome_-_high_mag.jpg