Category: Pharmacology

Leuprolide and flutamide

Leuprolide is a superactive GnRH (Gonadotropin releasing hormone) agonist. It can be given with flutamide for prostate cancer. Gonadotropin secretion occurs due to pulsatile secretion of GnRH. But when
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Ethinyl estradiol and norgestrel

Ethinyl estradiol and norgestrel are a combination of drugs used as hormonal contraceptive in women. Ethinyl estradiol is synthetic estrogen analogue and norgestrel is a synthetic progesterone analogue. Mechanism of action
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Linezolid

Linezolid is an oxazolidinone antimicrobial agent. It is a bacteriostatic agent. Spectrum of action MRSA (Methicillin resistant Staphylococcus areus), some VRSA (Vancomycin resistant Staphylococcus areus), VRE (Vancomycin resistant enterococci), Streptococcus
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Urinary antiseptics

Urinary antiseptics are antimicrobial agents. When these are given in orally tolerated doses, they attain antibacterial concentrations only in urine due to concentration in the renal tubules. These
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Isoniazid and pyridoxine

Isoniazid is an antituberculous drug. It can cause peripheral neuropathy and rarely convulsions by decreasing the availability of pyridoxine (vitamin B6). Isoniazid binds to pyridoxal-5-phosphate, the active form
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