PG Blazer

Albenadazole

It is an antihelminthic drug, a newer congener of mebendazole. Mechanism of action is same as that of mebendazole. It inhibits glucose uptake into the helminth’s cells and

Pharmacology

Metronidazole is a nitro-imidazole drug which has antiprotozoal and anti-anaerobe activity. Spectrum Protozoans – Entamoeba histolytic, Giardia lamblia, Trichomonas vaginalis Bacteria – Camphylobacter jejuni, Helicobacter pylori, Fusobacterium, Bacteriodes fragilis,

Pharmacology

Why is methylergometrine not used in the induction of labour?

Methylergometrine produces non-physiological spasmodic contraction of the uterus in moderate to high doses and the uterus does’nt fully relax between the contractions. It also causes contraction of the

Pharmacology

Adverse effects of corticosteroids

Produces Cushing’s habitus – moon face, supraclavicular hump, trunkal obesity and relatively thin limbs, hirsuitim. It causes proximal myopathy – shoulder, arms, hip, thigh Fragility and thinning of

Pharmacology

What is lactulose? Why is it preferred in patients with hepatic precoma?

Lactulose is a semi-synthetic disaccharide composed of fructose and galactose. It is not absorbed in the intestine. It is broken down into osmotically more active products by the

Pharmacology

Why are aminoglycosides not absorbed orally?

Aminoglycosides are highly ionised molecules and hence they are not absorbed orally.

Pharmacology

Advantages of doxycycline over other tetracyclines

High potency Completely absorbed from the intestine with no interference by food Long plasma half life (T 1/2) of 18 to 24 hours Least effect on the normal

Pathology

Karyotyping

Karyotyping is a method for studying the chromosomes of an organizm. Karyotype is a standardised arrangement of metaphasic chromosomes that have been photographed and arranged in the order

Pathology

Hyaline change

Hyaline change is a homogenous glassy pink appearance in the histological sections stained with hematoxylin and eosin. It can be due to intracellular accumulation of certain substances as

Latest